Molecular Biology Research Core Facility

The Molecular Biology Research Core Facility houses several shared/common equipments and machines for molecular sciences. The facility has one unit of TechGene and one unit of Biorad Conventional Thermal Cyclers. Furthermore, it also has a RotorGene 3000 Real Time PCR Machine (Qiagen) and CFX96 Real-Time PCR (Biorad). It also maintains a set up for Gel Electrophoresis and Gel Documentation System. The core facilities had its major renovations and is currently housing the latest facility on QiaCube Automated DNA Extraction Machine (Qiagen) and Agilent Bioanalyzer Automated Gel Electrophoresis. Currently, there are different researches that maximize the use of these facilities as the following:

  • Nucleic acid based methods for the detection of enteric infections, caused by Salmonella, Enteroaggregative Escherichia coli, Cryptosporidium parvum and C. hominis, Giardia lamblia, and other enteropathogens.
  • Dengue Virus detection and simultaneous serotyping.
  • Genetic profiling of resistance among Multiple Drug-Resistant Tuberculosis (MDR-TB)
  • Genetic profiling of circulating/seasonal and Avian Derived H1N1 Influenza Viruses
  • Molecular epidemiology of the leading causes of infections in the Philippines

Ongoing Projects

3-D Targets: The UK Philippines Dengue Diagnostics and Drug Targets Research Consortium

HIV Drug Resistance Surveillance Library and Development of Molecular Diagnostics for Drug-Resistance Detection- Part 1: Surveillance of Mutations for Acquired Drug Resistance

Dengue: Climate, Evolution and Transmission

Improving the Molecular Diagnostics of Drug Resistant Tuberculosis

Responding to the Philippine HIV epidemic: an HIV drug resistance surveillance library and development of molecular diagnostics for drug-resistance detection:Part 2: Analysis and prevalence of pre-treatment drug resistance



The UPM - IBBC is organizing a Training Program for Laboratory Biosafety and Biosecurity Officers to commence in the second quarter of 2016. The main objective of the program is to develop a pool of local trainers who will undertake advocacy and continuing education on laboratory biosafety and biosecurity. At the end of the training, the trainers are expected to be competent in the following areas:

*Biosafety and biosecurity risk assessment *Laboratory vivarium Biosafety and Biosecurity *Biocontainment practices and procedures *Biocontainment facilities *Use of safety equipment *Incident response procedures *Infectious substance transport *Biosafety program management *Management of transgenic materials *Regulatory framework of transgenic materials

The training will entail at least ten modules, each of which with duration of two weeks, scheduled on July 18-29, 2016; September 18- October 1, 2016; and November 20- December 3, 2016.

For more information please click the download link: Download