Dengue Program

The absence of vaccines for dengue infections prompts science to detect dengue infection on its earliest stage possible. Early symptoms of dengue virus infection mimic those of other flaviviral diseases thus early clinical diagnosis is not conclusive (WHO, 1997). Viral isolation in cell cultures, followed by direct detection using immunofluorescence (IF) is considered a definitive diagnostic test. However, these methods are time-consuming, laborious and resource-demanding (Samuel and Tiagi, 2006). Serological tests such as immunoblots using IgM offer faster alternatives; however, serological diagnosis requires paired sera collection and is, in general, less specific than diagnosis by culture (WHO, 1997). Nucleic acid based testing has replaced the majority of the viral detection methods because of its faster turn-around time, as well as offering higher A rapid and accurate simultaneous detection and serotyping

of dengue virus infection offers the advantage of rapid diagnosis in the clinical setting while providing sero-epidemiological surveillance information for public health officials in formulating and evaluating health policies.


See Also


Ongoing Projects

3-D Targets: The UK Philippines Dengue Diagnostics and Drug Targets Research Consortium

HIV Drug Resistance Surveillance Library and Development of Molecular Diagnostics for Drug-Resistance Detection- Part 1: Surveillance of Mutations for Acquired Drug Resistance

Dengue: Climate, Evolution and Transmission

Improving the Molecular Diagnostics of Drug Resistant Tuberculosis

Responding to the Philippine HIV epidemic: an HIV drug resistance surveillance library and development of molecular diagnostics for drug-resistance detection:Part 2: Analysis and prevalence of pre-treatment drug resistance

News

CALL FOR APPLICATIONS FOR TRAINING FOR BIOSAFETY OFFICERS

The UPM - IBBC is organizing a Training Program for Laboratory Biosafety and Biosecurity Officers to commence in the second quarter of 2016. The main objective of the program is to develop a pool of local trainers who will undertake advocacy and continuing education on laboratory biosafety and biosecurity. At the end of the training, the trainers are expected to be competent in the following areas:

*Biosafety and biosecurity risk assessment *Laboratory vivarium Biosafety and Biosecurity *Biocontainment practices and procedures *Biocontainment facilities *Use of safety equipment *Incident response procedures *Infectious substance transport *Biosafety program management *Management of transgenic materials *Regulatory framework of transgenic materials

The training will entail at least ten modules, each of which with duration of two weeks, scheduled on July 18-29, 2016; September 18- October 1, 2016; and November 20- December 3, 2016.

For more information please click the download link: Download